Kristen Bell (Veronica Mars)
Jamie Lee Curtis (Scream Queens)
Sigourney Weaver (Alien)
Odette Annabele (The Unborn)
Victor Garber (Legends of Tomorrow)
Betty White (Hot In Cleveland)
James Wolk (For A Good Time, Call…)
Kristin Chenoweth (Pushing Daisies)
Sean Wing (Forget Me Not)
Kyle Bornheimer (The Big Wedding)
Christine Lakin (Family Guy)
Patrick Duffy (Dallas)
Reginald VelJohnson (Mike & Molly)
Jenna Leigh Green (Sabrina: The Teenage Witch)
Dwayne Johnson (Central Intelligence)
Cloris Leachman (Bad Santa)
In 2002, Marni Olsen (Kristen Bell) is an acne-riddled high school sophomore in Ridgecrest, California, with glasses and braces, making a video about how much she hates high school, and reveals how she is tormented and bullied by other children, specifically J-J the high school mean girl (Odette Yustman), who made Marni’s high school life miserable. She adds that her protective older brother, Will (James Wolk), was very popular as a handsome basketball player. However, at a very important basketball game, J-J pushes the mascot (Marni), who runs into Will, resulting in a loss of the game.
Eight years later, in 2010, she is a successful public relations executive in Los Angeles, recently promoted to a job in New York. When she returns to Ridgecrest to her attend her older brother’s Georgia King (Kristin Chenoweth) planned wedding, she discovers that Will is about to marry a girl named Joanna, who happens to be J-J. When Marni meets Joanna for the first time in eight years, Joanna seems not to recognize her. Marni is also upset to see that Joanna fits in very well with the family. The plot thickens when Marni’s mother Gail (Jamie Lee Curtis) meets up with Joanna’s aunt Ramona (Sigourney Weaver), Gail’s former best friend who pushed her into a pool at their senior prom. Ramona is now a successful, wealthy woman who owns several hotels and a private plane.
Although Gail seems willing to put the past behind her, she still feels the need to “outdo” Ramona during their interactions together. On the other hand, Marni is unwilling to forget the things Joanna did to her in high school, unless she apologizes, and decides to try to let her brother know of Joanna’s bullying past. Her attempts to get Will alone for a conversation fail. When Marni tells Joanna that she knows who she really is, it is obvious that Joanna remembers Marni. She refuses to give Marni a meaningful apology, and treats her disrespectfully, leaving Marni convinced that Joanna has not changed. Meanwhile, Gail comes to Ramona’s hotel room for “closure” about anything bad between them that happened in the past. They appear to make up, but Ramona still seems not to be too fond of Gail.
One day on the street, Will and Marni’s grandmother Bunny (Betty White) meet a man named Tim (Kyle Bornheimer). Joanna reveals that they have dated, and Tim appears devastated when he hears that she’s marrying Will. Marni decides to bring Tim to the rehearsal dinner as part of her plan to stop the wedding. When it is time for guests to make a toast to the bride and groom, Tim unexpectedly jumps up to give his toast to Joanna. He reveals to a stunned wedding party that Joanna left him at the altar. Later, a video is presented (recovered by Marni) from their old high school time capsule. The video reveals Joanna confessing who she was in high school: an alpha-female bully, with the footage showing proof of her tormenting Marni and other students. As the video is showing her ruining Will’s basketball game; Will unplugs the video projector before the video is complete and walks out, furious.
Marni is in trouble when everyone discovers that she was responsible for the video at the rehearsal dinner. Joanna’s defense for pretending not to remember Marni is: “I thought we could start over.” Marni is now convinced that Joanna hasn’t changed, and walks away. Joanna then starts a fight with Marni, who fights back. Will walks in and witnesses the fight. He confronts Joanna, calling her a bully and a liar and then scolds Marni for starting the mess behind his back. Joanna tries to reason with Will but he doesn’t care about her past and is furious that she lied to him.
Ramona and Gail argue after the rehearsal dinner, and Ramona accuses Gail of trying to ruin her life throughout high school. A fight ensues, with both of them falling into the pool. Ramona reveals that she had a grudge with Gail, even when they were best friends, because she always competed with and outdid her, culminating with Gail taking the boy that Ramona wanted to the prom. Ramona stated that Gail was already a legendary head cheerleader and prom queen, and drama was supposed to be hers, yet Gail also defeated her with the auditions. She sarcastically thanks Gail for what she did, because it motivated her to become successful in life. Gail apologizes for being insensitive, but reveals that she is proud of Ramona, and that her loving family is her accomplishment. Ramona, remorseful of her actions, reveals that she was just jealous of Gail’s happy family especially that her marriages didn’t work out, and feared that Gail was trying to take Joanna away from her. The two are hugging in the pool when Gail’s husband, Mark (Victor Garber), shows up. At home, he says that he is disgusted with the wedding and weekend being a disaster and grounds Marni and Gail, despite protest.
Later that night, Marni finds Joanna in the kitchen binging on junk food. She finally admits to Marni that she feels truly awful for bullying and tormenting her and feels like a terrible person, and that she loves Will and his entire family. She explained that when she found out that Marni is her fiance’s sister, she panicked and decided to pretend not to remember her. Marni forgives her and promises to get them back together. Marni apologizes to Will for her actions, saying she was only trying to protect him.
Joanna and Will reconcile in the family’s old tree house, but it collapses and injures both of them. Marni and Will’s little brother, Ben (Billy Unger), loosened the screws as a part of his plan in hiding the tree house because Will was going to move it as a wedding present. They are both forced to stay at a hospital, which delays the wedding. However, Marni puts together a makeshift wedding at the hospital, with the bride and groom bandaged, but properly dressed and able to walk down the aisle. Gail has a surprise for Ramona, it’s Richie Phillips (Patrick Duffy), the boy from high school that Ramona wanted to go to the prom with. Richie welcomes Ramona home and wants to be her date for the wedding, which makes Ramona very happy and they appear to start a relationship. Marni appears to start a relationship with Charlie (Sean Wing), her brother’s best friend who has always been kind to her. Joanna introduces Marni’s grandmother Bunny to an elderly woman, Helen Sullivan (Cloris Leachman). Unfortunately Helen and Bunny were rivals in high school when Helen stole a boy from her. Bunny gets her revenge when she cuts in on Helen’s dance and takes her partner. At the wedding reception, Marni presents her wedding gift to Will and Joanna—Hall & Oates in person performing Will and Joanna’s favorite and special song, “Kiss on My List” (as the movie’s couples, each share kisses—Will and Joanna, Marni and Charlie, Gail and Mark, Ramona and Richie, and Georgia forces a kiss from Tim). Everyone then joins Hall & Oates on stage.Kristen Bell Vs. Odette Annable and Jamie Lee Curtis Vs. Sigourney Weaver? Get ready for one heck of a hilarious showdown. You Again is written so well and you can see this through the comedy, as there is non stop laughter and a lot of cringy moments between the characters.